Preliminary lab tests showed that functionalized magnetic beads productively lowered blood levels of a destructive molecule that is raised during preeclampsia, as per to a new study. Preeclampsia is a problem of pregnancy distinguished by kidney dysfunction and hypertension that impacts an estimated 6% to 8% of women in the U.S. who give birth every year. Preeclampsia is also responsible for severe difficulties for the mother (stroke, seizures, liver dysfunction, renal failure) and the infant (preterm delivery, low birth weight, stillbirth). The situation also increases a woman’s peril for cardiovascular disease in further life (high blood pressure and stroke). Presently, there is no treatment for preeclampsia, and only childbirth can ease the symptoms. The study was published in the AHA’s (American Heart Association) journal Hypertension.
Scientists aimed at a molecule—known as sFlt-1—which is discharged by the placenta in the woman’s bloodstream and increases to higher levels in preeclampsia. Higher levels of sFlt-1 are accountable for blood vessel wall dysfunction, endowing to high blood pressure and for cornering two important molecules that improve blood vessel wall function known as VEGF (vascular endothelial growth factor) and PlGF (placenta growth factor). By using blood from women having preeclampsia, scientists conducted lab tests to observe if magnetic beads can essentially drag sFlt-1 out of the passage, therefore discharging up levels of VEGF and PIGF. They discovered that magnetic beads lowered sFlt-1 by almost 40% and released up to two times extra PIGF, lowering the sFlt-1 and PlGF ratio by 63%.
Recently, the AHA was in news for its study that stated that Arsenic in drinking water might alter heart structure. Drinking water that is infected with arsenic might cause to thickening of the heart’s most important pumping chamber in young adults. This is a structural change that surges the jeopardy for prospect heart problems, as per to new study. The research was published in Circulation: Cardiovascular Imaging.